Yoseph Barash, Ph.D.

Yoseph Barash, Ph.D.

Associate Professor of Genetics (Penn Medicine)

BioCiphers Lab

We focus on understanding RNA biogensis, its regulation, and its role in human disease and in phenotipic diversity. Much of our work involves modeling alternative splicing regulation and non-coding regulatory elements in the 5’/3′ UTR. The lab works in three main directions that pose computational, engineering, and experimental challenges:

  • Deriving new mechanistic insights into RNA biogenesis.

  • Applying our predictive algorithms for RNA processing to the study of human disease and phenotipic diversity.

  • Developing software tools that allow the greater scientific community to employ our algorithms.