Peter Klein, Ph.D.
Professor of Medicine (Hematology-Oncology) (Penn Medicine)
The Klein lab is studying the role of GSK-3 in splicing factor function in normal hematopoiesis, MDS, and leukemia. We are currently focusing on how pathogenic splicing factor mutations alter mitochondrial function and how this can be targeted therapeutically.
Keywords: splicing, GSK-3, Wnt, leukemia, mitophagy