Mohamad-Gabriel Alameh, Ph.D.

Mohamad-Gabriel Alameh, Ph.D.

Assistant Professor (Incoming), Department of Pathology and Laboratory Medicine (CHOP)

Our lab is focused on understanding the structure-activity relationships (SARs) of nucleic acid delivery systems and their associated adjuvant properties to improve the safety, reactogenicity, and potency of emerging mRNA therapeutics. 

We aim to apply these insights in developing mRNA-based vaccines against bacterial pathogens, especially those with urgent threat designations across regions of the world including low- and middle-income countries (LMICs). Our approach involves engineering novel delivery systems and their payloads for cell and tissue-specific treatments.