Lan Lin, Ph.D.
Assistant Professor of Pathology and Laboratory Medicine (Penn Medicine)
The Lin Lab studies RNA modifications (“epitranscriptomics”) in human health and disease. Post-transcriptional RNA processing and modifications are key mechanisms for gene regulation and functional diversity in eukaryotic cells. We develop and apply high-throughput sequencing strategies and transcriptome engineering technologies to study the regulation and function of RNA modifications, including alternative splicing, A-to-I RNA editing, and m6A RNA methylation. We also develop and apply omics technologies for RNA-based diagnostics and therapeutics.